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Similarly, in the CCK2RG q complex, the last seven amino acids of the G q -5 helix extensively interacts with V88 2.38 and T89 2.39 of TM2, R152 3.50 , A155 3.53 , and I156 3.54 of TM3, Q166 ICL2 at ICL2, L245 5.65 of TM5, V331 6.33 and L335 6.37 of TM6, and H394 8.47 at the TM7Helix8 hinge in CCK2R (Fig
Methods: We followed the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-analyses and used the PubMed, LILACS, and Cochrane databases, Google Scholar, and article references, irrespective of publication time